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Hepatitis means inflammation of the liver. Hepatitis C is a virus which may lead to cirrhosis (scarring of the liver) and liver cancer if left untreated. It is the leading reason for liver transplantation in the United States. There are 3.2 million people in the U.S. infected with it, and 50% of those people do not even know they have it. Most of the time, people have no symptoms. Symptoms which sometimes occur include fatigue, nausea, a poor appetite, weakness, weight loss, and muscle or joint pain.